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Visit Jerry Verlinger's column >>

JERRY VERLINGER

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Trying to get in the middle of everything!
Articles Posted: 133  Links Seeded: 2575
Member Since: 2/2008  Last Seen: 5/16/2012

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Rare Sharing of Data Leads to Progress on Alzheimer's

Seeded on Fri Aug 13, 2010 6:34 AM EDT
Read ArticleArticle Source: The New York Times
health, universities, food-and-drug-administration, national-institutes-of-health, human-brain, alzheimer-s, health-scientists, collaborative-effort-biological-markers, drug-and-medical-imaging-industries, progression-of-alzheimer-s-disease
Seeded by Jerry Verlinger
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In 2003, a group of scientists and executives from the National Institutes of Health, the Food and Drug Administration, the drug and medical-imaging industries, universities and nonprofit groups joined in a project that experts say had no precedent: a collaborative effort to find the biological markers that show the progression of Alzheimer's disease in the human brain.

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  • Groups: Activism, Good News Week., Historical Vine, Open Mic, Open Minded, rationalists, RightsVine, Science And Technology, SexVine, Successful Solutions
  • Regions: New York
  • Public Discussion (13)
Jerry Verlinger

Aaaah ............ hmmmm ........I uh.... I had a comment to make ....... but I can't remember what it was.

  • 4 votes
Reply#1 - Fri Aug 13, 2010 6:38 AM EDT
rottlady

Ha! Jerry, I was all ready to make some kind of serious comment here and then I read yours. I can't quit laughing now! You are too funny!

  • 5 votes
#1.1 - Fri Aug 13, 2010 9:49 AM EDT
JCAtom

Makes you wonder why this is a new or rare idea. Seems like a no-brainer.

  • 3 votes
#1.2 - Fri Aug 13, 2010 10:50 AM EDT
neenie1991

no precedent: a collaborative effort

Good grief. JC is right. Somebody hit them with a DUH hammer.

  • 3 votes
#1.3 - Fri Aug 13, 2010 11:02 AM EDT
Tacitus13

Makes you wonder why this is a new or rare idea. Seems like a no-brainer.

I understand that many in the R&D community are working for private companies but you would think scientists would know the benefits of working together on projects like this...

  • 3 votes
#1.4 - Fri Aug 13, 2010 10:37 PM EDT
Jerry Verlinger

Oh.... I remember now.

Everybody wants to be the first to announce a breakthrough. Scientist are very secretive (paranoid actually) about their research. They are afraid someone will steal their findings, or "spin off" from their findings and get undeserved credit for a breakthrough.

Writing a paper on a medical research breakthrough, and having it published in a publication such as the "New England Journal of Medicine", can greatly enhance the stature of a scientist. Also, it makes it easier to receive grants making it possible to conduct further research.

  • 4 votes
#1.5 - Sat Aug 14, 2010 12:55 AM EDT
JCAtom

Meanwhile, people with Alzheimer's progressively decline and fade from this world.

  • 5 votes
#1.6 - Sat Aug 14, 2010 10:45 AM EDT
Reply
Jerry Verlinger

Actually JC, the group has decided to collaborate regarding Alzheimer's research.

Hopefully they will find success in this effort and be encouraged to share medical research more often.

I didn't intend to make light of Alzheimer's in Cmmt #1, my mother suffers from Alzheimer's and everytime I forget to put the milk back in the refrig (which is everytime) I think about the decease.

Decease, illness, injury and death are all a part of this fragile thing we call life. For me, humor is the one way to help make life's tragedies more bearable.

Furthermore, .......................... hmmmmm ......... never mind.

(Damn! Did I forget to take my memory pills again?)

  • 3 votes
Reply#2 - Sat Aug 14, 2010 1:02 PM EDT
JCAtom

Yes, I understand what you were saying and am glad that these scientists are collaborating. Was commenting on the drive to be the first which can slow the progress that is the true goal of research such as this--not offended in the slightest by the humor, sorry if I gave that impression.

  • 2 votes
#2.1 - Mon Aug 16, 2010 11:39 AM EDT
Jerry Verlinger

Was commenting on the drive to be the first which can slow the progress that is the true goal of research such as this

Actually sometimes collaboration can slow things down, because these guys like to check and double check everything. When there are too many fingers in the pot, the double checking becomes cumbersome, arguments break out and progress is hindered.

These guys are driven, when they work alone they sometimes work around the clock. There has always been a debate in the research community about independent work vs collaboration.

I should have put the comment about humor in a separate post. It occurred to me that some people might think I was not serious about the issue, like Rottlady who was taken aback by the humor, made a comment about it, but then did not post her thoughts about Alzheimer's, so the comment was meant as a general notation.

No problem JC Thank you for your input.

  • 1 vote
#2.2 - Mon Aug 16, 2010 11:58 AM EDT
JCAtom

Thank you, great seed. Was about to seed it myself & you'd already gotten there!

  • 1 vote
#2.3 - Mon Aug 16, 2010 12:25 PM EDT
Physicist-retired

Jerry,

I’ve been giving this article a lot of thought since I read it yesterday. The approach is highly commendable, but there are so many barriers to extending it to other areas of research.

I think that it would be easy to make the case that the moral imperative to solve Alzheimer’s was a strong driver in setting up and maintaining the approach take here. That same moral imperative could be directed towards building collaborative efforts to address HIV/AIDS, basic cancer research, and possibly other critical issues. Hopefully, it will be.

But when the moral imperative is removed, there are significant problems with this approach in terms of the way both our scientific and R&D systems are set up.

For example, research funding and academic tenure are largely based on one’s original research (and publishing). If one spent three years doing research, putting the basic data ‘out there’, another researcher may be able to draw conclusions from that data, and publish based on it. In such a case, the original researcher would only be mentioned as ‘contributing’. Under our current system, this would lend nothing towards advancing his/her career, either in terms of achieving tenure or obtaining research funding.

It isn’t entirely selfish on the part of the researcher. His/her ability to do any real work is based on tenure and funding.

Of course, the hurdles against companies R&D units sharing data don’t even need to be explained.

In other words, the system is set up to prevent this kind of collaboration. And it’s very unfortunate, because it could be applied to so many other problems we face now. Maybe it’s time to rethink the system.

An excellent seed, and one that made me think. Thanks!

    #2.4 - Mon Aug 16, 2010 12:31 PM EDT
    Jerry Verlinger

    For example, research funding and academic tenure are largely based on one’s original research (and publishing).

    Thanks PR, your comment clarifies and expands on my comment #1.5

    This rivalry and need for secrecy in research has been going on for centuries. There are many incidents in history where the wrong scientist got credit for a discovery.

    Although there are ways to protect one from direct plagiarism, as you state in your comment "another researcher may be able to draw conclusions from that data, and publish based on it. In such a case, the original researcher would only be mentioned as ‘contributing’." how many times has THAT happened?!

    I'm glad the article gave you food for thought, and thank you for your input.

      #2.5 - Mon Aug 16, 2010 1:23 PM EDT
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